Course Experts: Jennifer Espiritu, PharmD, BCOP, CCRP

Course Description: This course reviews basic genomic principles relevant to oncology, interprets patient-specific genomic profiles, and discusses significance of select mutations and their potential as therapeutic targets.

[DFCI_KEYWORDS] Pharmacogenomics, Germline Mutations, Somatic Mutations, BRCA, Oncogenic Mutations, Gain of Function, Loss of Function, DNA Transcription, RNA Translation, Codons, Point Mutations, Missense Mutations, Silent Mutations, Nonsense Mutations, Frameshift Mutations, Amplification, HER2, Chromosomal Rearrangement, Microsatellite Instability, Tumor Mutational Burden (TMB)